lymphotoxin (lt) meaning in English
淋巴毒素
Examples
- Lymphotoxin ( lt ) is a kind of pleiotropic lymphocyte - secreted cytokine which mediates a large variety of inflammatory , immunostimulatory , and antiviral responses . in order to increase the antitumor activity of lymphotoxin and reduce its side effects , the recombinant plasmid pet36b - lt 27 was constructed to express soluble fusion protein cbd - lt 27 . the active form of lt 27 could be collected directly with several simple steps by three kind of components on the expressed fusion protein
本研究通过构建表达n端缺失27个氨基酸的淋巴毒素融合蛋白的重组质粒,在大肠杆菌中实现融合蛋白的可溶及分泌表达,同时利用表达载体上的几种特殊序列经简单的分离纯化步骤直接获得大量的有生物活性的淋巴毒素缺失体lt 27 ,为寻找一种高抗肿瘤活性、低临床毒副作用的生物抗癌药物进行了有效的探索。